Although the metabolism of heparin is complex, it may, for the purpose of choosing a protamine dose, be assumed to have a half-life of about 1/2 hour after intravenous injection. Administration of protamine sulfate can cause severe hypotensive and anaphylactoid reactions.
What are side effects of heparin?
Heparin side effects
bruising more easily.
bleeding that takes longer to stop.
irritation, pain, redness, or sores at the injection site.
allergic reactions, such as hives, chills, and fever.
increased liver enzymes on liver function test results.
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