mechanism of action

2022-02-13 09:25:09

chondroitin has been shown to supplement the structure of joint soft tissue structure by oral administration, clinically taking chondroitin can effectively relieve the pain and inflammation of arthritis, and has the effect of delaying joint aging.

human clinical trials have shown that oral chondroitin can increase the secretion of joint fluid and the concentration of hyaluronic acid , a lubricant between joints, while reducing the activity of chondroitin decomposition enzymes, delaying the degeneration of osteoarthres, and clinically there are also direct injections of hyaluronic acid into the joints to delay the deterioration of degenerative arthritis, taking chondroitin to increase the concentration of hyaluronic acid between joints, which is similar to the effect expected by this medical behavior.

According to the conclusions of several human clinical studies on oral chondroitin sulfide in recent years, the improvement effect of chondroitin in arthritis clinical symptoms is about 50% higher than that of people taking non-steroidal analgesic anti-inflammatory drugs (NSAIDs), and in the overall medical evaluation, the treatment effect is at least 25% higher than that of the population that does not use chondroitin or glucosamine (see the introduction of glucosamine), while the arthritis population using chondroitin and glucosamine alone is at least 25% higher in the overall medical evaluation. The improvement in clinical symptoms was comparable (39-40%), although the population using chondroitin alone tended to be slightly higher by 1%, and the combined use of chondroitin and glucosamine was significantly higher than the clinical effect of either ingredient alone by about 7-20%.

there are also some clinical studies on the prevention and treatment of chondroitin in the prevention and treatment of arteriosclerosis, experimental results show that the proportion of acute attacks in patients with coronary artery sclerosis who take 2000 mg of chondroitin sulfide every day is only 1.7% (1/60), compared with the control group of patients with arteriosclerosis who do not take chondroitin, it is about 27% (16/60) of the acute coronary heart attack rate, as for the role of chondroitin in the prevention and treatment of cardiovascular disease, there is no clear result, but the study shows that people who have been on a high-fat diet taking chondroitin sulfide for a long time seem to have a lower rate of increase in blood fat than in groups that do not take chondroitin sulfide, and at the same time have the effect of reducing thrombosis.

in addition, chondroitin is also one of the components of the blood vessel wall, is not chondroitin at the same time has the role of repairing blood vessels because of blood fat deposition caused by damage to the wall, and reduce the thrombotic aggregation reaction caused by the uneven surface of the wall, these mechanisms may be chondroitin to reduce the acute incidence of coronary heart disease, but the biochemical medical community still needs further research to confirm the real effect of chondroitin in the prevention of cardiovascular disease.