the difference between heparin, heparin sodium, and heparin calcium

2022-02-15 14:30:18

first, the concept

1. HEPARIN: HEPARIN WAS FIRST FOUND FROM THE LIVER AND NAMED, CONSISTING OF GLUCOAMINE, L-AIDUCURONOSIN, N-ACETYLGLUCIDE AND D-GLUCURONIC ACID ALTERNATELY COMPOSED OF MUCOPOLYSACCHARIDE SULFATE, WITH AN AVERAGE MOLECULAR WEIGHT OF 15KD.

2. heparin sodium: heparin sodium can interfere with many links of the blood coagulation process, and has anticoagulant effects inside and outside the body.

3. heparin calcium: a drug to prevent blood clot formation during hemodialysis.

second. uses

1. heparin: clinically it is mainly used for thromboembolic diseases, myocardial infarction, cardiovascular surgery, cardiac catheterization, extracorporeal circulation, hemodialysis, etc.

2. HEPARIN SODIUM: PREVENT THROMBOSIS AND EMBOLISM, TREAT DISSEMINATED INTRAVASCULAR COAGULATION (DIC) CAUSED BY VARIOUS CAUSES, AND OTHER IN VIVO AND IN VITRO ANTICOAGULANT.

3. heparin calcium: make anticoagulant and thrombotic drugs.

third. nature

1. heparin: it is strongly acidic, exists in the lungs, blood vessel walls, intestinal mucosa and other tissues, and is a natural anticoagulant substance in animals. hygroscopic, sodium salts can be stored at room temperature for at least 12 months.

2. HEPARIN SODIUM: MAINLY THROUGH THE COMBINATION WITH ANTITHROMBIN III. (AT-III.), AND ENHANCE THE INHIBITION OF THE LATTER ON THE ACTIVATION OF II., IX., X, XI. AND XII. COAGULATION FACTORS, THE CONSEQUENCES OF WHICH INVOLVE PREVENTING PLATELET AGGLUTINATION AND DESTRUCTION, HINDERING THE FORMATION OF THROMBOREGASE, PREVENTING PROTHROMBIN FROM BECOMING THROMBIN, INHIBITING THRO