GMP heparin production China

2021-07-23 09:09:38

What is the use of heparin?

Heparin is a powerful blood coagulant, studies in recent years have shown that heparin sodium also has the effect of lowering blood lipids.

Heparin is a naturally occurring acidic mucopolysaccharide, linear anionic polyelectrolyte.It is a family of compounds composed of chains of different structures and strong negative charges.It has the effect of prolonging the clotting time of the blood.

Heparin is a water soluble substance made up of a variety of heparins of different molecular weights, with a molecular weight of approximately 3000 to 50,000 Daltons.

Medicinal heparin is extracted from the intestinal lining of pigs or cattle, so allergic reactions can occur. The 2000 pharmacopoeia stipulated that the potency of heparin sodium should not be less than 150 units per 1 mg.

The heparin biological standard is expressed by the number of units equivalent to each milligram of heparin preparation (60 ° C. 2 mmHg column for drying under vacuum for 3 hours). 1μ is the minimum amount of heparin required to prevent 1 ml of cat blood from clotting in a cold place within 24 hours.

Heparin is first obtained from the liver, but is more abundant in the lungs. Heparin and proteins in the animal's body are combined in a complex form, so that they do not exhibit an anticoagulant effect.

Yantai Dongcheng Pharmaceutical Group Co.,GMP heparin manufacture, Ltd. (formerly known as “Yantai Dongcheng Biochemical Co., Ltd.) was established in 1998 and listed on the Shenzhen Stock Exchange (stock code: 002675) in May 2012. After over 20 years of development, Yantai Dongcheng Pharmaceutical Group Co., Ltd. has become a large pharmaceutical group covering four fields: biochemical APIs, chemical medicines, proprietary Chinese medicines and nuclide drugs, which integrates the research and development, production and sales of medicines.